Magnus Kjærgaard
Magnus is an associate professor at Aarhus University and an expert on the biophysics of intrinsically disordered proteins. He leads both his own research group and the “Biophysics and Biochemistry Core Facility”, and he is thus involved in a broad range of projects requiring advanced biophysical instrumentation.
The group’s primary focus is on enzymatic reactions in biomolecular condensates and disordered proteins that regulate synaptic plasticity.
Favourite Applications
Liquid-Liquid Phase Separation
Take full control of your condensates. Labbot can help you fine-tune solution conditions and map out phase behavior in unrivaled detail, giving you a better understanding of how droplets come and go.
There is no experimental readout that works for all proteins. We prefer to have as many options in our hands as possible when we have to set up assays for a new protein. Having Absorbance, Fluorescence and Light scattering packed into a single instrument gives us more flexibility when designing assays.
Labbot is an optical instrument designed with biochemical and biophysical measurements in mind. Many other instruments try to optimize e.g. spectral resolution, which is typically not that critical in our experiments. Instead, it is baked into the Labbot design that you will be doing a series of measurements as a function of time, temperature, concentration etc. This is really where the instrument shines.