Applications
What can You Investigate with Labbot?
Here are some of the most used ones.
Liquid-Liquid Phase Separation
Take full control of your condensates. Labbot can help you fine-tune solution conditions and map out phase behavior in unrivaled detail, giving you a better understanding of how droplets come and go.
Protein Interactions
Take classical methods to new heights with automated measurements. Detect ligand binding or oligomerization with FRET or by tracking changes in intrinsic fluorescence.
Amyloid Aggregation
Maximize the information obtained from each sample and untangle the complexities of fibril growth. By combining full spectrum readouts with light scattering and exercising complete control over sample conditions, you can easily set up your next amyloid experiment.
Thermal Stability
Follow protein unfolding with intrinsic fluorescence or external probes while Labbot scans temperature across your defined range. Easily track any resulting aggregation with static light scattering for a full thermal profile of your protein.
Metal Ion Binding
Labbot's automated titration provides detailed binding curves for a deeper understanding of protein-metal ion interactions. You can obtain your measurement output via absorbance or fluorescence spectroscopy, depending on your assay's needs.
pH Stability
Labbot collects real-time data from an attached pH meter for highly detailed pH titrations, including measuring the isoelectric point of a protein, mapping pH-dependent phase behaviors, or monitoring other pH-affected processes.